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Obesity is associated with increased morbidity and mortality, and obesity prevalence is >40% in the United States. Obesity management has beneficial effects on a wide range of weight-related conditions, making it a critical component of comprehensive healthcare. Primary care professionals (PCPs) manage most of the adult population in the United States, so they need to be prepared to manage obesity as a chronic disease, toward preventing or improving weight-related conditions and overall health. This downloadable slideset includes current guidance, expert perspectives, and key evidence on obesity management for PCPs.